Can a new injection plus a pill tame ulcerative colitis?
NCT ID NCT07768254
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This early trial is testing whether a new investigational drug called HX15001, given as an injection, can be safely combined with an existing pill (etrasimod) to treat moderate-to-severe ulcerative colitis. The study will include about 32 adults with the condition and will focus on safety, tolerability, and how the drug moves through the body, while also looking at preliminary signs of effectiveness. The goal is to see if this combination approach might offer a new way to control the disease and its symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HX15001 injection combined with etrasimod tablets
- What this could lead to
- If successful, this combination could offer a new treatment option for people with moderate-to-severe ulcerative colitis, potentially reducing symptoms and improving quality of life.
- What could go wrong
- This is an early, small exploratory trial focused on safety and dosing, so it may not lead to a proven treatment. There are also risks of side effects from the new drug and the existing medication.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The first affiliated hospital of Anhui medical university
Hefei, Anhui, 230022, China
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