Gut bacteria shifts after bariatric surgery: a clue to better weight loss?

NCT ID NCT07277465

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 60 obese patients who had bariatric surgery (like gastric bypass or sleeve gastrectomy). Researchers checked their gut bacteria and hormone levels before and 6-12 months after surgery. The goal was to see how the microbiome changes and if those changes relate to metabolic health or sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bariatric surgery (gastric bypass, sleeve gastrectomy, or SADI-S)

What this could lead to

If successful, this could reveal how gut bacteria affect weight loss and metabolic health after bariatric surgery, pointing toward future microbiome-based treatments for obesity.

What could go wrong

This is a small, completed observational study with no treatment being tested, so results may not apply broadly. It only looks at changes, not whether those changes cause health improvements.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic syndrome X Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • FISABIO

    Valencia, 46017, Spain