Gut bacteria shifts after bariatric surgery: a clue to better weight loss?

NCT ID NCT07277465

Completed Knowledge-focused Sponsor: Celia Bañuls Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 60 obese patients who had bariatric surgery (like gastric bypass or sleeve gastrectomy). Researchers checked their gut bacteria and hormone levels before and 6-12 months after surgery. The goal was to see how the microbiome changes and if those changes relate to metabolic health or sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bariatric surgery (gastric bypass, sleeve gastrectomy, or SADI-S)
What this could lead to: If successful, this could reveal how gut bacteria affect weight loss and metabolic health after bariatric surgery, pointing toward future microbiome-based treatments for obesity.
What could go wrong: This is a small, completed observational study with no treatment being tested, so results may not apply broadly. It only looks at changes, not whether those changes cause health improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic syndrome X Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESE PATIENTS WITH BARIATRIC SURGERY

Contacts and locations

Locations

FISABIO

Valencia, 46017, Spain

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