Gut bacteria test could revolutionize colon cancer screening
NCT ID NCT06588166
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to develop a new, non-invasive diagnostic tool for colorectal cancer by analyzing gut microbiome signatures in stool samples. Researchers will enroll 1006 participants aged 50-74 who have tested positive on the standard fecal immunochemical test (FIT). By combining clinical data with microbial analysis using machine learning, they hope to create a scoring system that more accurately identifies cancer and advanced adenomas, potentially reducing the number of unnecessary colonoscopies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gut microbiome testing
What this could lead to
If successful, this could provide a more accurate, non-invasive screening test for colorectal cancer, potentially reducing unnecessary colonoscopies.
What could go wrong
This is an observational study, not a treatment trial. The tool is still being developed and validated, so it may not prove accurate enough for widespread use.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Agostino Gemelli, IRCCS
RECRUITINGRoma, 00168, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••