Spinal injury study tracks Gut-Brain talk after eating

NCT ID NCT07052344

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Recruiting now This study
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Expanded access (not trials)

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First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study looks at how food changes the connection between the brain and stomach in people with and without spinal cord injury. Researchers will measure brain and stomach signals in 28 adults to understand gut-brain communication. The goal is to learn more about how spinal cord injury affects this link, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria, SCI and Controls * Adults, 18 to 70 years of age. * Sex, male or female. * Weight-stable (±3 kg) for the preceding 3 months (self-report). * Physically inactive adults not meeting weekly activity guidelines (\<150 min/week) for the preceding 3 months (self-report). * Fluent in written and spoken English. Exclusion Criteria, SCI and Controls * Do not meet the inclusion criteria. * Current/regular smoker (defined by Center for Disease Control (CDC)/ National Institute of Health (NIH) as an adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes either every day or every other day) (self-report). * Currently dieting and/or trying to gain or lose weight. * Vagus or recurrent laryngeal nerve injury (self-report). * Uncontrolled thyroid disease, such that they are not on thyroid medication (e.g., levothyroxine) to treat the condition (self-report) * Diabetes (type 1 or type 2) and/or currently taking anti-diabetic or glucagon-like peptide-1 (GLP-1)/dual agonist medications (self-report). * Gastrointestinal disease (self-report), such as inflammatory bowel disease (e.g. Crohn's disease, ulcerative colitis), celiac disease, irritable bowel syndrome, gastroesophageal reflux disease, peptic ulcer disease, chronic pancreatitis, liver cirrhosis, and any condition requiring gastrointestinal surgery (e.g., bowel resection, colostomy, or ileostomy). * Swallowing disorder (self-report). * History of bariatric surgery * Food allergies/dislikes or dietary restrictions (i.e. vegan) (self-report). * Allergy to adhesives (self-report) * Open abdominal wounds or abdominal skin not intact. * Current use of probiotics/prebiotics (self-report). * Current use of medications that can impact appetite, body weight, and/or bowel function, such as prokinetic, antiemetic, narcotic analgesics, anticholinergic, anti-inflammatory, antipsychotic, or anti-obesity agents (self-report). * Pregnant (determined by urine pregnancy test) or breastfeeding women. * Non-adults (infants, children, teenagers). * Adults unable to consent * Prisoner. SCI-specific Eligibility Criteria Inclusion Criteria, SCI Only * At least 12 months post-SCI, denoting chronic injury * Complete American Spinal Injury Association (ASIA) Impairment Scale (AIS A) or motor-incomplete (AIS B) tetraplegia (SCI at or above C8 lesion) * Able to self-feed (self-report) * On a bowel care program every day or every other day (self-report). Exclusion Criteria, SCI Only * Under 12 months post-SCI. * Motor-incomplete (AIS C, D) paraplegia (SCI below C8 lesion), including thoracic, lumbar, and sacral injuries. * Ventilator-dependence (self-report).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Miami - Miami Project to Cure Paralysis

    RECRUITING

    Miami, Florida, 33136, United States

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