Gut bacteria and fiber fermentation: key to understanding IBS?

NCT ID NCT06668922

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how gut bacteria and diet affect symptoms in people with irritable bowel syndrome (IBS). Researchers will measure bile acids, short-chain fatty acids, and gut microbes in stool samples from 72 adults with IBS and healthy volunteers after a controlled diet. Participants will also take inulin, a fiber supplement, to see how well their gut bacteria ferment it. The goal is to find links between gut bacteria, diet, and IBS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Inulin (a dietary fiber supplement used to test fermentation, not to treat IBS)

What this could lead to

If successful, this study could help explain how gut bacteria and diet contribute to IBS symptoms, potentially pointing toward personalized dietary recommendations.

What could go wrong

This is an observational, early-stage study with only 72 participants. It does not test a treatment, so results may not lead to direct therapies or apply to all IBS patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••