Could an Anti-Inflammatory diet designed for Crohn's disease also tame IBS?
NCT ID NCT07707635
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This study tests whether a modified version of the Crohn's Disease Exclusion Diet (CDED) can ease symptoms of non-constipation irritable bowel syndrome (IBS) better than the standard low FODMAP diet. About 150 adults with moderate-to-severe IBS will follow one of the two diets for six weeks. Researchers will track symptom changes, gut inflammation, and microbiome health to see if the CDED offers added benefits beyond symptom relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a modified Crohn's Disease Exclusion Diet (CDED) adapted for IBS, excluding the enteral formula
- What this could lead to
- If effective, the modified CDED could offer a new dietary option for people with IBS that targets inflammation and gut health, potentially improving symptoms and quality of life.
- What could go wrong
- This is a relatively small, early-stage study, and the modified CDED may not prove superior to the standard low FODMAP diet. Dietary interventions can be hard to follow, and results may not apply to everyone with IBS.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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