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Can laser or Air-Polishing boost gum disease treatment?

NCT ID NCT07788937

Disease control Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This trial compares three ways to treat stage 3 periodontitis, a severe form of gum disease that damages the tissue and bone supporting teeth. Researchers will give 60 adults either standard deep cleaning alone, deep cleaning plus diode laser therapy, or deep cleaning plus guided biofilm therapy, which uses air and powder to remove plaque. They will measure gum health, bone levels, and inflammatory markers in fluid around the teeth before and after treatment to see if the added methods improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Non-surgical periodontal therapy with or without adjunctive diode laser or guided biofilm therapy
What this could lead to
If adding these techniques works, it could lead to better gum disease control and less bone damage for people with advanced periodontitis.
What could go wrong
The trial is small and early, so results may not apply to everyone. The added treatments might not provide extra benefit over standard care, and laser or air-polishing could cause temporary gum irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Aug 2023

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years. * Diagnosis of Stage III periodontitis with clinical attachment loss (CAL) ≥5 mm, probing pocket depth (PPD) ≥6 mm, and radiographic bone loss extending to the middle or apical third of the root. * Systemically healthy individuals. * Non-smokers and non-alcohol users. * No periodontal treatment within the previous 6 months. * No history of destructive periodontal disease. * Not pregnant or breastfeeding. * Written informed consent provided. Exclusion Criteria: * Age \<18 years or \>65 years. * Periodontitis other than Stage III. * Presence of systemic diseases affecting periodontal health. * Current smokers or alcohol users. * Periodontal treatment within the previous 6 months. * History of destructive periodontal disease. * Pregnancy or breastfeeding. * Inability or unwillingness to provide written informed consent.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis Periodontitis (stage 3)

Contacts and locations

Locations

  • Department of Periodontology, Faculty of Dentistry, Ataturk University

    Erzurum, 25240, Turkey (Türkiye)

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