Simple handgrip exercise may cut clot risk for PICC patients

NCT ID NCT06370702

ENROLLING_BY_INVITATION Prevention Sponsor: TriHealth Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a simple handgrip exercise can lower the risk of deep vein thrombosis (DVT) in adult hospital patients with a PICC line. Participants squeeze a soft ball for 10 seconds, rest, and repeat for 10 minutes, three times a day. The trial will track 2,500 patients to see if this easy activity reduces clot rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: handgrip exercises
What this could lead to: If it works, this simple exercise could become a low-cost way to prevent dangerous blood clots in patients with PICC lines.
What could go wrong: This is the first study of its kind in the US, so there is no prior evidence yet. The exercises may not reduce clot risk, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP VEIN THROMBOSIS

Contacts and locations

Locations

Bethesda North Hospital

Cincinnati, Ohio, 45242, United States
Good Samaritan Hospital

Cincinnati, Ohio, 45220, United States

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