Can brain chemistry predict who benefits from stimulation?
NCT ID NCT07196423
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study investigates how the brain chemical glutamate relates to memory and attention in people who have recently experienced psychosis. Researchers will use brain scans and a mild electrical stimulation technique called tDCS to see if glutamate levels can predict who responds to stimulation. The goal is to better understand brain chemistry and potentially tailor future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If successful, this could lead to a way to predict which patients with psychosis will benefit from brain stimulation, allowing more personalized treatment.
What could go wrong
This is an early-stage study with only 106 participants, focused on understanding brain chemistry rather than testing a treatment. The findings may not lead to immediate clinical changes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Nottingham
RECRUITINGNottingham, Nottinghamshire, NG7 2RD, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••