New gel could stop tooth pain after fillings

NCT ID NCT07188142

Not yet recruiting Symptom relief Sponsor: Beenish Hassan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether applying Gluma desensitizer before a filling can reduce tooth sensitivity afterward. Sixty adults with cavities in their back teeth will be randomly assigned to get either the desensitizer plus a standard filling or just the standard filling. Their pain response to an air puff will be measured right after the procedure and again at 1 week, 1 month, and 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Gluma Desensitizer (glutaraldehyde/HEMA solution)
What this could lead to: If it works, this could give dentists a simple way to reduce tooth pain after fillings, making the procedure more comfortable for patients.
What could go wrong: This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The treatment is for temporary sensitivity, not a cure for tooth decay.

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Conditions

The condition(s) this trial relates to.

dental caries dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL CARIES DENTIN HYPERSENSITIVITY POST-OPERATIVE SENSITIVITY POST-OPERATIVE SENSITIVITY AFTER CLASS I COMPOSITE RESTORATIONS TOOTH SENSITIVITY AFTER COMPOSITE RESTORATIONS

Contacts and locations

Locations

Margalla Institute of Health Sciences Quaid e Azam Avenue, Gulraiz phase 3, Gulraiz Housing Scheme, Rawalpindi

Rawalpindi, Punjab Province, Pakistan

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