Could a diabetes drug shield the brain? early trial targets cognitive decline

NCT ID NCT06171152

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-phase study looks at whether liraglutide (Saxenda®), a drug used for weight loss, can increase a brain-protective protein called BDNF in people with multiple sclerosis, long-COVID, or acute leukemia (in remission) who also have obesity and memory or thinking problems. About 30 participants will take the drug for 8 weeks, with follow-up blood tests to measure BDNF levels. The goal is to gather initial data on whether this approach might help protect the brain, not to treat the underlying diseases.

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Contacts and locations

Locations

  • University of Chicago Medicine Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.