Brain scans may reveal how to protect memory during radiation

NCT ID NCT04975139

Ongoing Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 71 glioma patients before and after radiation therapy to see how their thinking skills change. Researchers use special brain scans (RS-fMRI) to map which brain networks are most harmed by radiation. The goal is to learn which areas to avoid during treatment planning to preserve cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors plan radiation therapy to better protect brain areas responsible for memory and thinking in glioma patients.
What could go wrong: This is an early observational study with only 71 participants. It does not test a treatment, so it may not lead to immediate changes in patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign neoplasm of brain glioma IDH-mutant anaplastic astrocytoma oligodendroglioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

Locations

Washington University School of Medicine

St Louis, Missouri, 63110, United States

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