New radiation technique tested for aggressive brain cancer

NCT ID NCT01507506

Terminated Disease control Sponsor: Institut Claudius Regaud Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tested two types of radiation therapy for glioblastoma, a fast-growing brain tumor. One group received standard 3D radiation, while the other got a more precise intensity-modulated radiation guided by MRI scans. Both groups also took the chemotherapy drug temozolomide. The study aimed to see if the newer radiation method could help patients live longer. However, the trial was stopped early, so we don't have full results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Temozolomide (chemotherapy) and radiotherapy (radiation)
What this could lead to: If successful, this could show that a more precise radiation technique improves survival for people with glioblastoma.
What could go wrong: The trial was terminated early, so results are limited. It is unclear if the experimental approach is better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA

Contacts and locations

Locations

AP HM - Hôpital La Timone

Marseille, 13385, France
CHU de Strasbourg

Strasbourg, 67065, France
Centre Georges François Leclerc

Dijon, 21000, France
Centre Jean Perrin

Clermont-Ferrand, 63011, France
Centre Leon Berard

Lyon, 69373, France
Centre Marie Curie

Valence, 26953, France
Centre Paul Strauss

Strasbourg, 67065, France
Centre Val d'Aurelle

Montpellier, 34298, France
Clinique Claude Bernard

Albi, 81000, France
Hospices Civils de Lyon (Hôpital Lyon Sud/Hôpital P. Wertheimer)

Lyon, 69002, France
Institut Claudius REGAUD

Toulouse, 31052, France
Institut de Cancerologie Lucien Neuwirth

Saint-Priest-en-Jarez, 42271, France

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