Scientists hunt for genes that spark brain inflammation in Alzheimer's

NCT ID NCT04840979

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at how certain genes influence the activity of immune cells in the brain, called microglia, in people with Alzheimer's disease. Researchers will use a special PET scan to measure these cells in about 107 older adults, some with mild memory problems or Alzheimer's and some healthy. The goal is to find which gene variants cause microglial activation, which may help understand how Alzheimer's progresses.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States