Gene hunt for kidney disease FSGS aims to explain racial disparities

NCT ID NCT00001393

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study searched for genetic factors that may cause focal segmental glomerulosclerosis (FSGS), a kidney disease that can lead to kidney failure. Researchers compared DNA from 616 people, including African-Americans with FSGS, African-Americans with HIV but no FSGS, and non-African-Americans with FSGS. The goal was to find genes that increase risk, which could lead to earlier detection and better treatments in the future.

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Conditions

The condition(s) this trial relates to.

focal segmental glomerulosclerosis HIV-associated nephropathy kidney disorder sporadic idiopathic steroid-resistant nephrotic syndrome with collapsing glomerulopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States