DNA collection study aims to unlock secrets of rare liver diseases

NCT ID NCT05272319

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study collected blood or saliva samples from 213 people with rare liver diseases to extract and store their DNA. The goal was to create a genetic resource that scientists can use in future studies to explore the causes, biomarkers, and genetic factors of these conditions. Participants were children and adults previously enrolled in other liver disease research studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this DNA repository could help researchers better understand the genetic causes of rare liver diseases and identify new biomarkers or treatment targets.

What could go wrong

This is a sample collection study, not a treatment trial. It does not test any therapy, and the DNA resource may or may not lead to future medical advances.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90027, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Riley Hospital for Children

    Indianapolis, Indiana, 46202, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Texas Children's Hospital; Baylor College of Medicine

    Houston, Texas, 77030, United States

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1XG, Canada

  • UCSF Benioff Children's Hospital

    San Francisco, California, 94143, United States

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • University of Utah

    Salt Lake City, Utah, 84113, United States