11,000 volunteers help unlock genetic secrets of heart valve disease
NCT ID NCT01026571
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is looking for the genetic causes of bicuspid aortic valve disease, a common heart condition where the aortic valve has two flaps instead of three. Researchers will analyze DNA from 11,000 participants, including patients and their relatives, to find gene changes linked to the disease. The goal is to better understand why it happens and who is at risk.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Medical Center
Boston, Massachusetts, 02118, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- 6,464 patients join global hunt for bicuspid valve genes
- Hunt for heart valve genes launches in 700 volunteers
- Less invasive heart valve replacement put to the test against Open-Heart surgery
- Scientists hunt for hidden genes behind aortic aneurysms
- Scientists hunt for genetic clues to aortic aneurysm risk