A new way to size heart valves: could the 'circle method' reduce TAVI complications?

NCT ID NCT05844969

Completed Knowledge-focused Sponsor: Institut für Pharmakologie und Präventive Medizin Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This study looks at whether the 'circle method' — a way to measure the aortic valve — can help doctors choose the right size replacement valve for people with bicuspid aortic valves who are getting a TAVI procedure. Researchers will review past cases to see if patients whose valve size matched the circle method had fewer complications. The goal is to develop better sizing guidelines for this challenging condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If validated, the circle method could help doctors select the optimal valve size for TAVI in patients with bicuspid aortic valves, potentially reducing complications.
What could go wrong: This is a retrospective analysis of existing data, not a prospective trial. The findings may not apply to all patients or valve types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve disease 1 aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS WITH BICUSPID VALVE

Contacts and locations

Locations

Guy's and St Thomas NHS Foundation Trust

London, SE17EH, United Kingdom
Royal Papworth Hospital NHS Foundation Trust

Cambridge, CB20AY, United Kingdom
The Essex Cardiothoracic Centre

Basildon, England, SS16 5NL, United Kingdom
University Hospitals Sussex NHS Foundation Trust

Worthing, BN112DH, United Kingdom

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