6,464 patients join global hunt for bicuspid valve genes

NCT ID NCT01980797

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study gathers genetic and health information from over 6,400 people with bicuspid aortic valve, a common heart defect. Researchers aim to find the genes responsible for the condition and why some patients later develop serious aortic disease. No treatment is given; the goal is to better understand and predict the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bicuspid Aortic Valve Disease familial bicuspid aortic valve

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center

    Boston, Massachusetts, 02218, United States

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Istituto Policlinico San Donato

    San Donato Milanese, Milan, 20097, Italy

  • Laval University

    Québec, Quebec, G1V 4G5, Canada

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Monaldi Hospital

    Naples, 80100, Italy

  • Second University of Naples

    Naples, 80131, Italy

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Oxford

    Oxford, OX3 9DU, United Kingdom

  • University of Salerno

    Salerno, 36-83023, Italy

  • University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States