Short bursts of low oxygen may boost breathing after spinal injury

NCT ID NCT06011876

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether short episodes of breathing low-oxygen air can improve breathing strength in people with chronic spinal cord injury. Participants will try three different breathing sessions (low oxygen, low oxygen with extra carbon dioxide, and normal air) to see which works best. Researchers will also look for genetic differences that might explain why some people respond better than others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acute Intermittent Hypoxia (AIH) and Acute Intermittent Hypercapnic-Hypoxia (AIHH)

What this could lead to

If successful, this could point toward a personalized breathing therapy for people with spinal cord injury based on their genetics.

What could go wrong

This is an early, small study (62 people) focused on short-term changes, not long-term outcomes. Results may not apply to everyone with spinal cord injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Respiratory Aspiration spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brooks Rehabilitation

    RECRUITING

    Jacksonville, Florida, 32216, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••