New gene therapy attack on deadly brain cancer

NCT ID NCT03603405

First seen Apr 06, 2026 · Last updated Apr 16, 2026 · Updated 2 times

Summary

This study is testing whether adding a new gene therapy to standard radiation and chemotherapy can help people newly diagnosed with aggressive brain tumors (anaplastic astrocytoma or glioblastoma). The gene therapy involves injecting a modified virus into the tumor during surgery, followed by an oral antiviral drug, aiming to kill cancer cells. Researchers will monitor 62 participants to see if this combination is safe and improves survival compared to standard treatment alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Houston Methodist Neurological Institute

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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