Gene therapy trial aims to boost HIV fight in lymphoma patients

NCT ID NCT02337985

First seen Nov 10, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This early-stage trial tests whether adding gene therapy to standard chemotherapy can help people with AIDS-related lymphoma fight both cancer and HIV. Ten participants receive chemotherapy followed by an infusion of their own blood stem cells modified with anti-HIV genes. The main goal is to check safety and see if the gene-modified cells survive in the body.

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Contacts and locations

Locations

  • NCI Lymphoid Malignancies Branch

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.