Gene test may help men with prostate cancer skip treatment safely

NCT ID NCT04396808

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a special gene test can help men with low-risk prostate cancer decide to monitor their cancer instead of treating it right away. About 805 men with early-stage prostate cancer will be randomly assigned to have the gene test or not. The goal is to see if the test helps more men safely choose active surveillance (watchful waiting) without their cancer getting worse.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Sherwood Medical Center

    Detroit, Michigan, 48221, United States

  • Spectrum Health Medical Group

    Grand Rapids, Michigan, 49503, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania Perelman School of Medicine

    Philadelphia, Pennsylvania, 19104, United States

  • Western Michigan Urological Associates

    Holland, Michigan, 49423, United States