New study targets colorectal cancer in underrepresented minorities

NCT ID NCT06562543

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This phase 4 trial is testing the safety and effectiveness of the oral drug fruquintinib in 78 adults from minority groups (Black/African American and Hispanic/Latino) with advanced colorectal cancer that hasn't responded to other treatments. The main focus is on how often high blood pressure occurs as a side effect. Participants take fruquintinib in 4-week cycles until their disease worsens or side effects become too much.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fruquintinib (Fruzaqla™)
What this could lead to: If successful, this could show that fruquintinib is safe and effective for minority patients with advanced colorectal cancer, helping to address gaps in treatment knowledge.
What could go wrong: This is a small, single-arm study with no comparison group, so results may not be definitive. Hypertension is a known side effect, and the trial may not lead to new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Albert Einstein College of Medicine
WITHDRAWN

The Bronx, New York, 10461, United States
BRCR Global
WITHDRAWN

Katy, Texas, 77450, United States
Baptist Health - Miami Cancer Institute
WITHDRAWN

Miami, Florida, 33176, United States
Baylor College of Medicine
RECRUITING

Houston, Texas, 77054, United States
Boston Medical Center
WITHDRAWN

Boston, Massachusetts, 02118, United States
Capital Health Medical Center - Hopewell
RECRUITING

Pennington, New Jersey, 08534, United States
Central Alabama Research
RECRUITING

Birmingham, Alabama, 35209, United States
Christiana Care Health Services
RECRUITING

Newark, Delaware, 19713, United States
Columbia University
WITHDRAWN

New York, New York, 10032, United States
Emory University
RECRUITING

Atlanta, Georgia, 30322, United States
Fox Chase Cancer Center | Philadelphia, PA
WITHDRAWN

Philadelphia, Pennsylvania, 19111, United States
Fundacion de Investigacion de Diego (FDI Clinical Research)
COMPLETED

San Juan, 00927, Puerto Rico
Hattiesburg Clinic
RECRUITING

Hattiesburg, Mississippi, 39401, United States
Hightower Clinical Research
COMPLETED

Oklahoma City, Oklahoma, 73102, United States
Hope and Healing Cancer Services
RECRUITING

Hinsdale, Illinois, 60521, United States
Indiana University
RECRUITING

Indianapolis, Indiana, 46202, United States
Ironwood Cancer and Research Centers
RECRUITING

Chandler, Arizona, 85224, United States
James J Peters Veterans Administration Medical Center - NAVREF
WITHDRAWN

The Bronx, New York, 10468, United States
Jefferson Health
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
Medical University of South Carolina
WITHDRAWN

Charleston, South Carolina, 29425, United States
Medstar Speciality Hospital
RECRUITING

Northwest, Washington, 20010, United States
Mercy Medical Center
RECRUITING

Baltimore, Maryland, 21202, United States
Midwest Oncology Associates - Kansas City
RECRUITING

Kansas City, Missouri, 64132, United States
Oncology Consultants - Memorial City Location
RECRUITING

Houston, Texas, 77030, United States
Our Lady of the Lake Physician Group - LSU Health Baton Rouge Oncology
RECRUITING

Baton Rouge, Louisiana, 70805, United States
PIH Health Whittier Hospital
RECRUITING

Whittier, California, 90602, United States
Renovatio Clinical
RECRUITING

El Paso, Texas, 79915, United States
Renovatio Clinical
RECRUITING

The Woodlands, Texas, 77380, United States
SSM Health St. Louis DePaul Hospital
RECRUITING

St Louis, Missouri, 63044, United States
Saint Luke's Cancer Institute
WITHDRAWN

Kansas City, Missouri, 64111, United States
Tranquil Research
RECRUITING

Webster, Texas, 77598, United States
UC Irvine Medical Center - Chao Family Comprehensive Cancer
RECRUITING

Orange, Virginia, 22960, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35249, United States
University of Arizona
RECRUITING

Tucson, Arizona, 85719, United States
University of California San Diego
RECRUITING

La Jolla, California, 92093, United States
University of Florida
COMPLETED

Gainesville, Florida, 32610, United States
University of Miami
WITHDRAWN

Miami, Florida, 33146, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States
University of Tennessee -- Memphis
RECRUITING

Memphis, Tennessee, 38163, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37212, United States
Virginia Commonwealth University
RECRUITING

Richmond, Virginia, 23298, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63108, United States
Willis Knighton Cancer Center
RECRUITING

Shreveport, Louisiana, 71103, United States
Zangmeister Cancer Center
RECRUITING

Columbus, Ohio, 43219, United States

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