New study targets colorectal cancer in underrepresented minorities
NCT ID NCT06562543
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 4 trial is testing the safety and effectiveness of the oral drug fruquintinib in 78 adults from minority groups (Black/African American and Hispanic/Latino) with advanced colorectal cancer that hasn't responded to other treatments. The main focus is on how often high blood pressure occurs as a side effect. Participants take fruquintinib in 4-week cycles until their disease worsens or side effects become too much.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fruquintinib (Fruzaqla™)
What this could lead to
If successful, this could show that fruquintinib is safe and effective for minority patients with advanced colorectal cancer, helping to address gaps in treatment knowledge.
What could go wrong
This is a small, single-arm study with no comparison group, so results may not be definitive. Hypertension is a known side effect, and the trial may not lead to new treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Albert Einstein College of Medicine
WITHDRAWNThe Bronx, New York, 10461, United States
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BRCR Global
WITHDRAWNKaty, Texas, 77450, United States
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Baptist Health - Miami Cancer Institute
WITHDRAWNMiami, Florida, 33176, United States
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77054, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Boston Medical Center
WITHDRAWNBoston, Massachusetts, 02118, United States
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Capital Health Medical Center - Hopewell
RECRUITINGPennington, New Jersey, 08534, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Central Alabama Research
RECRUITINGBirmingham, Alabama, 35209, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Christiana Care Health Services
RECRUITINGNewark, Delaware, 19713, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University
WITHDRAWNNew York, New York, 10032, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fox Chase Cancer Center | Philadelphia, PA
WITHDRAWNPhiladelphia, Pennsylvania, 19111, United States
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Fundacion de Investigacion de Diego (FDI Clinical Research)
COMPLETEDSan Juan, 00927, Puerto Rico
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Hattiesburg Clinic
RECRUITINGHattiesburg, Mississippi, 39401, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hightower Clinical Research
COMPLETEDOklahoma City, Oklahoma, 73102, United States
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Hope and Healing Cancer Services
RECRUITINGHinsdale, Illinois, 60521, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ironwood Cancer and Research Centers
RECRUITINGChandler, Arizona, 85224, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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James J Peters Veterans Administration Medical Center - NAVREF
WITHDRAWNThe Bronx, New York, 10468, United States
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Jefferson Health
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medical University of South Carolina
WITHDRAWNCharleston, South Carolina, 29425, United States
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Medstar Speciality Hospital
RECRUITINGNorthwest, Washington, 20010, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mercy Medical Center
RECRUITINGBaltimore, Maryland, 21202, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Midwest Oncology Associates - Kansas City
RECRUITINGKansas City, Missouri, 64132, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oncology Consultants - Memorial City Location
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Our Lady of the Lake Physician Group - LSU Health Baton Rouge Oncology
RECRUITINGBaton Rouge, Louisiana, 70805, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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PIH Health Whittier Hospital
RECRUITINGWhittier, California, 90602, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renovatio Clinical
RECRUITINGEl Paso, Texas, 79915, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renovatio Clinical
RECRUITINGThe Woodlands, Texas, 77380, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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SSM Health St. Louis DePaul Hospital
RECRUITINGSt Louis, Missouri, 63044, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Saint Luke's Cancer Institute
WITHDRAWNKansas City, Missouri, 64111, United States
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Tranquil Research
RECRUITINGWebster, Texas, 77598, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UC Irvine Medical Center - Chao Family Comprehensive Cancer
RECRUITINGOrange, Virginia, 22960, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35249, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Arizona
RECRUITINGTucson, Arizona, 85719, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Diego
RECRUITINGLa Jolla, California, 92093, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Miami
WITHDRAWNMiami, Florida, 33146, United States
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University of Southern California
RECRUITINGLos Angeles, California, 90033, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Tennessee -- Memphis
RECRUITINGMemphis, Tennessee, 38163, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63108, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Willis Knighton Cancer Center
RECRUITINGShreveport, Louisiana, 71103, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zangmeister Cancer Center
RECRUITINGColumbus, Ohio, 43219, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••