Tailored chemo doses could boost GI cancer treatment

NCT ID NCT05780684

Recruiting now Disease control Sponsor: Dartmouth-Hitchcock Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new way to give chemotherapy for gastrointestinal cancers like colorectal and stomach cancer. Doctors will adjust the dose of one chemo drug (5-FU) based on how well each patient tolerates it, aiming to give higher doses to those who can handle it without severe side effects. The goal is to see if this personalized approach is feasible and effective. About 36 adults with advanced or inoperable cancers will participate.

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Conditions

The condition(s) this trial relates to.

appendiceal neoplasm appendix cancer carcinoma of the ampulla of vater colorectal cancer colorectal neoplasm digestive system cancer digestive system carcinoma esophageal cancer Esophageal Neoplasms small intestine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMPULLARY CANCER APPENDIX CANCER COLORECTAL CANCER ESOPHAGUS CANCER SMALL BOWEL CANCER

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Dartmouth-Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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