Single antibiotic dose may prevent Post-Surgery infections as well as a 5-Day course
NCT ID NCT07355907
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a single dose of the antibiotic fosfomycin trometamol could prevent infections after kidney stone surgery as effectively as a 5-day course of levofloxacin. 210 adults undergoing surgery were randomly assigned to one of the two treatments or a control group. The goal was to see which approach better reduced post-surgery infections and sepsis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fosfomycin trometamol and levofloxacin
- What this could lead to
- If successful, a single dose of fosfomycin could replace longer antibiotic courses to prevent infections after kidney stone surgery.
- What could go wrong
- This is a completed trial with 210 participants, so results are available but may not apply to all patients or settings. Antibiotic resistance or side effects remain possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of medicine, Tanta University
Tanta, 11511, Egypt
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