Sound waves aim to stop stubborn seizures in ICU patients

NCT ID NCT05784805

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 21 times

Summary

This study tests a non-invasive technique called pulsed low-intensity focused ultrasound (PLIFU) to reduce seizure activity in people with a severe, ongoing seizure condition called status epilepticus that hasn't improved with standard medications. Ten participants in the ICU will receive a 10-minute ultrasound session targeting brain areas involved in seizures. The goal is to see if this approach can safely and quickly calm abnormal brain activity.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.