Ultrasound zaps a new brain spot to quiet Parkinson's tremors

NCT ID NCT06259708

Completed Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether low-intensity focused ultrasound aimed at a brain area called the zona incerta (ZI) can reduce tremors in 20 people with Parkinson's disease. Researchers compared this approach to the standard target (Vim) and used brain scans to understand how the treatment works. The goal is to find a better way to control tremors without surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: low intensity focused ultrasound (device)
What this could lead to: If successful, this could point toward a more effective brain target for ultrasound treatment of Parkinson's tremor.
What could go wrong: This is a small, early-stage study with only 20 participants, so results may not apply to everyone. The treatment is still experimental and may not work as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease Tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

University of British Columbia, DMCBH

Vancouver, British Columbia, V6T 1Z3, Canada

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Other studies related to the condition(s) this trial covers.