Poop pills: does donor selection make or break IBS treatment?
NCT ID NCT06171126
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether the donor of a fecal transplant affects IBS symptoms. 500 patients with moderate-to-severe IBS will receive either a placebo (their own stool) or stool from one of three different donors, delivered via a tube into the small intestine. They will track symptoms, quality of life, and gut bacteria changes over a year to see if donor selection leads to better outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fecal microbiota transplant (FMT) from selected donors
What this could lead to
If successful, this could show that choosing the right donor improves FMT outcomes for IBS, offering a more effective symptom relief option.
What could go wrong
This is a mid-sized trial, but FMT is still experimental for IBS. Results may vary, and long-term benefits or risks are not yet fully known.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Diakonhjemmet
Oslo, Norway
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Haukeland University Hospital
Bergen, Vestland, 5021, Norway
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Helse Møre og Romsdal HF
Ålesund, Norway