Could a statin and arthritis drug tame childhood brain cancer?
NCT ID NCT02115074
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tested a combination of two drugs—fluvastatin (a cholesterol-lowering statin) and celecoxib (an arthritis drug)—in 20 children and young adults with certain brain tumors (gliomas) that had come back or not responded to treatment. The goal was to find the safest dose of fluvastatin when given with a fixed dose of celecoxib, and to see if the combo could help control the disease. The study was completed, but results are not yet reported.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluvastatin and Celecoxib (Celebrex)
What this could lead to
If this works, it could point toward a new way to control certain childhood brain tumors without harsh side effects.
What could go wrong
This is a very early, small phase 1 trial with only 20 participants. It is designed to find a safe dose, not to prove the treatment works. The drugs may not shrink tumors or improve survival.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU Angers
Angers, 49933, France
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Centre Hospitalier de Nancy
Vandœuvre-lès-Nancy, 54511, France
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Centre Hospitalier de Purpan - Hôpital des Enfants
Toulouse, 31026, France
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Centre Hospitalier de Strasbourg
Strasbourg, 67098, France
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Centre Léon Bérard
Lyon, 69373, France
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Centre Oscar Lambret
Lille, 59020, France
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Hôpital pour enfants La Timone
Marseille, 13385, France
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Institut Curie
Paris, 75005, France