New algorithm aims to guide fluid treatment for kidney injury in cirrhosis patients
NCT ID NCT06525623
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a volume assessment guidance algorithm (VAGA) to help doctors decide how much and what type of IV fluid to give cirrhosis patients with acute kidney injury. Fifty hospitalized adults with cirrhosis and kidney injury will be randomly assigned to receive either VAGA-guided recommendations or standard IV albumin. The goal is to see if the algorithm is safe, practical, and effective at guiding fluid therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- IV fluids (crystalloid, colloid, or albumin) guided by a volume assessment algorithm
- What this could lead to
- If successful, this could provide a safer, more effective way to manage fluids for kidney injury in cirrhosis patients, potentially reducing complications.
- What could go wrong
- This is a small pilot study with only 50 participants, so results may not apply broadly. The algorithm may not improve outcomes over standard care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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