New algorithm aims to guide fluid treatment for kidney injury in cirrhosis patients
NCT ID NCT06525623
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a volume assessment guidance algorithm (VAGA) to help doctors decide how much and what type of IV fluid to give cirrhosis patients with acute kidney injury. Fifty hospitalized adults with cirrhosis and kidney injury will be randomly assigned to receive either VAGA-guided recommendations or standard IV albumin. The goal is to see if the algorithm is safe, practical, and effective at guiding fluid therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
IV fluids (crystalloid, colloid, or albumin) guided by a volume assessment algorithm
What this could lead to
If successful, this could provide a safer, more effective way to manage fluids for kidney injury in cirrhosis patients, potentially reducing complications.
What could go wrong
This is a small pilot study with only 50 participants, so results may not apply broadly. The algorithm may not improve outcomes over standard care.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••