Stool test could ease cancer screening for lynch syndrome patients

NCT ID NCT06898996

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a fecal immunochemical test (FIT), which checks for blood in the stool, can accurately detect colorectal cancer in people with Lynch Syndrome. Lynch Syndrome increases the risk of colorectal cancer, and patients currently need regular colonoscopies. The study will compare FIT results to colonoscopy findings in 400 participants to see how well the simpler test works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal immunochemical test (FIT)

What this could lead to

If successful, this could offer a less invasive, more convenient screening option for people with Lynch Syndrome, potentially reducing the need for frequent colonoscopies.

What could go wrong

This is an early-stage study focused on accuracy, not treatment. FIT may miss some cancers that colonoscopy would find, and results may not apply to all Lynch Syndrome patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60639, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••