Could a zap to your face lift your mood? new trial explores FES for depression

NCT ID NCT07629050

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether Functional Electrical Stimulation (FES) of facial muscles is a safe and effective way to reduce depression symptoms in people with major depressive disorder (MDD). About 60 adults with MDD who have not responded to up to two treatments will receive FES or a sham procedure. Researchers will measure changes in depression severity, anxiety, and well-being over 20 sessions.

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