Could a dye reveal hidden scarring in Crohn's patients?
NCT ID NCT07152431
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new imaging method using a special dye (FAPI) to detect bowel scarring in people with Crohn's disease. Scarring affects up to half of patients and often leads to surgery, but current tests can't spot it early. The study will involve 30 adults starting biologic treatment, who will receive PET/CT scans to see if the dye can track scarring activity. If it works, this could pave the way for new drugs that prevent permanent bowel damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FAPI (fibrosis associated protein inhibitor) dye used with PET/CT imaging
What this could lead to
If successful, this could be the first non-invasive way to detect and track bowel scarring in Crohn's disease, helping develop new anti-fibrotic treatments.
What could go wrong
This is a small, early observational study with only 30 participants. It tests a detection method, not a treatment, so it may not directly improve patient outcomes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NHS Lothian
RECRUITINGEdinburgh, United Kingdom
Contact