Scientists probe fat Tissue's secret life during weight gain

NCT ID NCT04583514

Recruiting now Knowledge-focused Sponsor: Pennington Biomedical Research Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how fat tissue changes when people gain weight from overeating. Researchers will ask 58 overweight adults to either maintain their weight or eat 30% more calories for a short time. By tracking fat cell growth and other changes, they hope to understand why some people develop health problems like diabetes from weight gain while others do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal why some people develop metabolic problems from weight gain while others do not.
What could go wrong: This is an early-stage observational study, not a treatment trial. Results may not lead to direct health benefits or apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Insulin Resistance metabolic syndrome X Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC SYNDROME OVERWEIGHT AND OBESITY

Contacts and locations

Locations

Pennington Biomedical Research Center
RECRUITING

Baton Rouge, Louisiana, 70809, United States

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