Experimental drug zervimesine made available to patients with lewy body dementia

NCT ID NCT06961760

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This expanded access program offers the experimental drug zervimesine (CT1812) to people aged 50 to 86 with mild-to-moderate dementia with Lewy bodies. Participants take one 100 mg pill daily for up to a year. The goal is to provide access to the drug and collect long-term safety information.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

zervimesine (CT1812)

What this could lead to

If this program shows that zervimesine is safe and well-tolerated over a year, it could support further research into a treatment for dementia with Lewy bodies.

What could go wrong

This is an expanded access program, not a formal trial, so it provides limited evidence of effectiveness. The drug is still experimental, and long-term risks are not fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dementia Lewy body dementia Lewy Body Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Banner Sun Health Research Institute

    Sun City, Arizona, 85351, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Mayo Clinic - Rochester

    Rochester, Minnesota, 55905, United States

  • Ohio State University Wexner Medical Center (OSUWMC)

    Columbus, Ohio, 43210, United States

  • Stanford Neuroscience Heath Center

    Palo Alto, California, 94304, United States

  • Summit Headlands LLC

    Portland, Oregon, 97210, United States

  • University of Colorado Denver - Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of Miami - Department of Neurology

    Boca Raton, Florida, 33433, United States