New drug access for low blood sugar after Weight-Loss surgery

NCT ID NCT07582874

AVAILABLE Disease control Sponsor: Amylyx Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This expanded access program offers avexitide to people with post-bariatric hypoglycemia (dangerously low blood sugar) after Roux-en-Y gastric bypass. Eligible patients include those who completed the LUCIDITY trial or other avexitide studies. Participants receive a daily injection before their first meal, and safety is monitored.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Avexitide (a drug injected under the skin once daily before the first meal)
What this could lead to: If it works, this could offer ongoing symptom control for people with dangerously low blood sugar after weight-loss surgery.
What could go wrong: This is an expanded access program, not a formal trial, so evidence is limited. The drug may not work for everyone, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dumping syndrome hypoglycemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST BARIATRIC HYPOGLYCEMIA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Centricity Research Morehead City Multispecialty
AVAILABLE

Morehead City, North Carolina, 28557-3126, United States
Diabetes and Glandular Disease Clinic
AVAILABLE

San Antonio, Texas, 78229-4801, United States
Joslin Diabetes Center
AVAILABLE

Boston, Massachusetts, 02215-5306, United States
Southern Endocrinology and Diabetes Associates
AVAILABLE

Mesquite, Texas, 75149, United States

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