Can exercise or brain games sharpen thinking in schizophrenia?

NCT ID NCT06572657

Completed Disease control Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether aerobic exercise or computerized cognitive stimulation could improve thinking skills in 58 adults with schizophrenia. Participants were randomly assigned to one of the two activities. The goal was to see which approach better boosts memory, attention, and problem-solving. The results could help guide simple, non-drug ways to support mental function in schizophrenia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aerobic exercise and computerized cognitive stimulation
What this could lead to: If successful, this could point toward a simple, drug-free way to help people with schizophrenia think more clearly and manage daily life better.
What could go wrong: This is a small, completed trial with only 58 participants, so results may not apply to everyone. It compares two non-drug approaches, so any benefit is likely modest and not a cure.

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Conditions

The condition(s) this trial relates to.

Motor Activity schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMPUTERIZED COGNITIVE STIMULATION EXERCISE SCHIZOPHRENIA

Contacts and locations

Locations

Kartal Dr Lütfi Kırdar Şehir Hastanesi

Istanbul, Turkey (Türkiye)

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