Blood thickens during exercise in rare disorder, study aims to find why

NCT ID NCT07341048

Not yet recruiting Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why people with polycythemia vera (PV), a rare blood disorder that makes too many red blood cells, often struggle with exercise. Researchers will measure blood thickness and oxygen levels in 54 patients during a treadmill stress test. The goal is to see if a big jump in blood thickness during exercise limits how much oxygen the body can use, which could explain exercise intolerance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors understand why exercise is hard for PV patients and design safer, more effective exercise plans.
What could go wrong: This is a small, early observational study (54 people) that only measures effects during one exercise test. It won't test any treatment, so it may not lead to direct improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired polycythemia vera polycythemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYTHEMIA POLYCYTHEMIA VERA (PV)

Contacts and locations

Locations

Department of Sports Medicine and Physical Activity. Pulmonary Function Testing. Croix Rousse Hospital.

Lyon, 69001, France

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