POLYCYTHEMIA VERA (PV)
Clinical trials for POLYCYTHEMIA VERA (PV) explained in plain language.
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New drug trial hopes to tame rare blood cancers
Disease control Recruiting nowThis early-phase study tests a new drug called PRT12396 in about 100 people with polycythemia vera or myelofibrosis, which are types of blood cancers. The main goals are to find a safe dose and see if the drug can help control the disease. Participants must have a specific gene m…
Matched conditions: POLYCYTHEMIA VERA (PV)
Phase: PHASE1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated May 17, 2026 03:43 UTC
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New pill may help control thick blood in Hard-to-Treat patients
Disease control Recruiting nowThis study tests a new drug called flonoltinib maleate in 60 people with polycythemia vera (a condition where the body makes too many red blood cells) who have not responded to or cannot tolerate standard treatments like hydroxyurea or interferon. The goal is to see if the drug c…
Matched conditions: POLYCYTHEMIA VERA (PV)
Phase: PHASE2 • Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd • Aim: Disease control
Last updated May 17, 2026 03:42 UTC
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Desperate patients gain access to promising drug through managed programs
Disease control AVAILABLEThis program provides access to the drug ruxolitinib (INC424) for patients with serious or life-threatening conditions like certain blood cancers, severe COVID-19, or graft-versus-host disease when no other treatments are available. It is for people who cannot join a clinical tri…
Matched conditions: POLYCYTHEMIA VERA (PV)
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Could a $10 arthritis pill tame rare blood cancers?
Disease control Recruiting nowThis study tests whether low-dose methotrexate (MTX), a safe and inexpensive drug used for decades in arthritis, can help people with certain blood cancers called myeloproliferative neoplasms (MPNs). The trial will enroll 54 adults with polycythemia vera, essential thrombocythemi…
Matched conditions: POLYCYTHEMIA VERA (PV)
Phase: PHASE2 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New drug aims to reduce Blood-Letting in rare blood cancer
Disease control Recruiting nowThis study tests an experimental drug called DISC-3405 in 60 adults with polycythemia vera (PV), a condition where the body makes too many red blood cells. The goal is to see if the drug is safe and can reduce the need for regular blood removal (phlebotomy). Participants will rec…
Matched conditions: POLYCYTHEMIA VERA (PV)
Phase: PHASE2 • Sponsor: Disc Medicine, Inc • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New registry aims to unlock secrets of rare blood cancers
Knowledge-focused Recruiting nowThis study follows 5,000 adults with myeloproliferative neoplasms (MPNs) — rare blood cancers — to understand how symptoms change and how the disease progresses over years. Participants share their health records, insurance data, and regular surveys about how they feel. No new tr…
Matched conditions: POLYCYTHEMIA VERA (PV)
Sponsor: MPN Research Foundation • Aim: Knowledge-focused
Last updated May 04, 2026 16:17 UTC