High vs. moderate exercise: which is better for the brain in diabetes?

NCT ID NCT06734546

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how different exercise intensities affect the brain in people with type 2 diabetes. 75 inactive adults aged 30-75 will do supervised cycling at high or moderate intensity for 6 months, three times a week. Researchers will use brain scans, cognitive tests, and blood samples to compare changes in brain metabolism, blood flow, and thinking skills against a non-exercising control group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exercise (high or moderate intensity)

What this could lead to

If successful, this could show which exercise intensity best protects brain health in type 2 diabetes, potentially guiding future prevention strategies for cognitive decline.

What could go wrong

This is a small, early-stage study (75 participants) focused on measuring brain changes, not treating disease. Results may not apply to all diabetes patients, and exercise adherence could vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for TYPE 2 DIABETES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

dementia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hasselt University

    RECRUITING

    Hasselt, Limburg, 3500, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact