High vs. moderate exercise: which is better for the brain in diabetes?

NCT ID NCT06734546

Recruiting now Knowledge-focused Sponsor: Hasselt University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how different exercise intensities affect the brain in people with type 2 diabetes. 75 inactive adults aged 30-75 will do supervised cycling at high or moderate intensity for 6 months, three times a week. Researchers will use brain scans, cognitive tests, and blood samples to compare changes in brain metabolism, blood flow, and thinking skills against a non-exercising control group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise (high or moderate intensity)
What this could lead to: If successful, this could show which exercise intensity best protects brain health in type 2 diabetes, potentially guiding future prevention strategies for cognitive decline.
What could go wrong: This is a small, early-stage study (75 participants) focused on measuring brain changes, not treating disease. Results may not apply to all diabetes patients, and exercise adherence could vary.

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Conditions

The condition(s) this trial relates to.

dementia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES

Contacts and locations

Locations

Hasselt University
RECRUITING

Hasselt, Limburg, 3500, Belgium

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