Can walking during chemo reduce side effects? new study aims to find the best dose

NCT ID NCT05789485

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing three different amounts of treadmill walking (90, 150, or 300 minutes per week) in people receiving chemotherapy for colorectal or stomach cancers. The goal is to find a safe and practical exercise level that helps patients complete their full chemotherapy plan with fewer side effects. The study will track how well participants tolerate treatment and whether exercise improves their overall health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

structured treadmill walking

What this could lead to

If successful, this could establish a recommended amount of aerobic exercise to help patients tolerate chemotherapy better and reduce side effects.

What could go wrong

This is a Phase 2 trial with 216 participants, so results are preliminary. Exercise may not benefit everyone, and some patients may find the walking schedule difficult to maintain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer digestive system cancer digestive system neoplasm gastroesophageal cancer Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hartford Healthcare Alliance (Data Collection Only)

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••