Can exercise plus a pill ease both knee pain and depression in seniors?
NCT ID NCT04111627
First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 23 times
Summary
This study looked at whether adding the drug duloxetine to a supervised aerobic exercise program could help older adults with both knee osteoarthritis and depression. All 43 participants received the combined treatment to see if it was feasible and if it improved pain and mood. The goal was to gather initial data for a larger future study.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Maryland School of Medicine
Baltimore, Maryland, 21201, United States
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