Implant could replace daily shots for obesity and diabetes

NCT ID NCT05670379

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tested a small implant placed under the skin that steadily releases a drug called exenatide, similar to popular weight-loss and diabetes medications. The goal was to check safety and how the drug behaves in the body. Twenty-four overweight but otherwise healthy adults took part, and the implant was compared to standard injections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exenatide implant (a drug-device combination that releases a GLP-1 receptor agonist under the skin)

What this could lead to

If successful, this implant could offer a long-lasting, convenient way to manage weight and blood sugar without daily injections.

What could go wrong

This is a very early Phase 1 trial with only 24 people, so safety and effectiveness are not yet proven. The implant may cause side effects or fail to work as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CMax

    Adelaide, Australia