Nerve pain device study abandoned after only 2 patients
NCT ID NCT04649554
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a device called Exablate, which uses focused sound waves to treat areas of the brain linked to pain. The goal was to see if it could reduce pain and improve quality of life in people with chronic nerve pain. Only 2 people enrolled before the study was stopped, so no meaningful results were obtained.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Exablate (MRgFUS) device
- What this could lead to
- If it had worked, this could point toward a non-invasive treatment for chronic nerve pain.
- What could go wrong
- The study was terminated early with only 2 participants, so no reliable conclusions can be drawn. The approach may not be effective or safe for broader use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NEUROPATHIC PAIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fondazione IRCCS Neurologico Carlo Besta
Milan, 20133, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a skin injection of ketamine and lidocaine tame CRPS pain?
- Could painkillers quietly disrupt your hormones?
- Alzheimer's drug may stop chronic pain after breast surgery
- Pepper-Based patch tested against Kids' chronic nerve pain
- Could a botox shot in the mouth silence stubborn nerve pain?
- Zapping pain without drugs: brain stimulation put to the test for nerve pain