Sleep apnea treatment may shield aging brains from memory loss

NCT ID NCT05988385

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether successfully treating moderate-to-severe sleep apnea can improve memory and reduce biological markers linked to Alzheimer's disease in older adults. About 200 cognitively healthy people aged 55-85 will either receive immediate sleep apnea treatment or join a waitlist, then be followed for two years. Researchers will measure changes in memory, brain chemicals, and thinking skills to see if better sleep leads to better brain health.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai

    RECRUITING

    New York, New York, 10023, United States

    Contact

    Contact

  • New York University

    RECRUITING

    New York, New York, 10016, United States

    Contact

    Contact

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85719, United States

    Contact

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact