New study aims to find best pain block for gallbladder surgery
NCT ID NCT06900413
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two types of nerve blocks—ESP and EXORA—for managing pain after laparoscopic gallbladder removal. Fifty-six adults having elective surgery will be randomly assigned to receive one of the blocks. The goal is to see which block provides better pain relief and reduces the need for additional painkillers in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic injection)
- What this could lead to
- If one block works better, it could become the standard for reducing pain after gallbladder surgery, helping patients recover faster with less medication.
- What could go wrong
- This is a small, early-stage trial with only 56 people. The results may not apply to everyone, and nerve blocks carry rare risks like infection or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 56 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age between 18 and 65 years Undergoing elective laparoscopic cholecystectomy Classified as American Society of Anesthesiologists (ASA) physical status I to III Providing written informed consent Exclusion Criteria: Known allergy or hypersensitivity to local anesthetics Infection or skin lesions at the site of block application Emergency surgical procedures Refusal to participate in the study Uncontrolled arterial hypertension Uncontrolled diabetes mellitus Mental retardation Current use of antidepressant medications Presence of metabolic disorders Known bleeding diathesis Morbid obesity (Body Mass Index \> 40 kg/m²)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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