Cure My Disease

Don't miss your cure!

 Log in / Sign up

Cooling probe may shield esophagus during heart ablation for AF

NCT ID NCT04577859

Completed Disease control Sponsor: Advanced Cooling Therapy LLC, d/b/a Attune Medical Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests whether a special cooling probe placed in the esophagus can protect it from heat damage during a common heart procedure for atrial fibrillation (AF). AF is a heart rhythm disorder that can cause serious symptoms, and ablation uses heat to fix it, but the esophagus sits close by and can be injured. The study compares the cooling probe to a standard temperature monitor in people undergoing AF ablation under general anesthesia, to see if cooling reduces esophageal injury and improves safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ensoETM esophageal cooling probe
What this could lead to
If it works, this could make AF ablation safer by reducing the risk of esophageal injury, a rare but serious complication.
What could go wrong
This is a mid-stage trial; the cooling probe may not prove better than standard care, and any device carries procedural risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AF - ATRIAL FIBRILLATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AF - ATRIAL FIBRILLATION ATRIO-ESOPHAGEAL FISTULA COMPLICATION

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Kansas City Cardiac Arrhythmia Research LLC

    Overland Park, Kansas, 66211, United States

  • NCH Research Institute

    Naples, Florida, 34102, United States

  • St.George's Hospital

    London, SW170QT, United Kingdom

  • Texas Cardiac Arrhythmia Research Foundation

    Austin, Texas, 78705, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.