Nerve block injection may ease back pain in ankylosing spondylitis patients

NCT ID NCT07633730

Recruiting now Symptom relief Sponsor: Marmara University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a single nerve block injection (erector spinae plane block) can reduce persistent back pain in people with ankylosing spondylitis whose disease activity is already controlled by medication. Fifteen adults aged 18–65 will receive the injection and be monitored for pain and mobility changes. It is an early, small trial without a placebo group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nerve block injection (bupivacaine, saline, dexamethasone)
What this could lead to: If it works, this could offer a new pain-relief option for people with ankylosing spondylitis who still have back pain despite standard treatment.
What could go wrong: This is a very small early study (15 people) with no comparison group, so results may not be reliable or apply to others. The block is temporary and not a cure.

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Conditions

The condition(s) this trial relates to.

ankylosing spondylitis Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANKYLOSING SPONDYLITIS (AS) BACK PAIN ESPB REGIONAL ANESTHESIA

Contacts and locations

Locations

Marmara University Faculty of Medicine Pendik Training and Research Hospital
RECRUITING

Istanbul, Pendik, Turkey (Türkiye)

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