New drug shows promise for Hard-to-Treat bladder cancer
NCT ID NCT02365597
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests a drug called erdafitinib in 239 people with advanced bladder cancer that has certain FGFR gene changes. The drug aims to shrink tumors by blocking signals that help cancer grow. Researchers are checking how well it works and what side effects occur.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Erdafitinib
What this could lead to
If successful, this could provide a new targeted treatment option for people with advanced bladder cancer that has specific genetic changes.
What could go wrong
This is a mid-stage trial, so the drug may not work for everyone or could have side effects. Results may not apply to all bladder cancer patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sedona, Arizona, United States
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Los Angeles, California, United States
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Orange, California, United States
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Sacramento, California, United States
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Stanford, California, United States
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Aurora, Colorado, United States
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Washington D.C., District of Columbia, United States
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Chicago, Illinois, United States
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Iowa City, Iowa, United States
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Louisville, Kentucky, United States
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Minneapolis, Minnesota, United States
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Omaha, Nebraska, United States
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Las Vegas, Nevada, United States
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New York, New York, United States
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Charlotte, North Carolina, United States
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Medford, Oregon, United States
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Tualatin, Oregon, United States
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Hershey, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Myrtle Beach, South Carolina, United States
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Nashville, Tennessee, United States
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Dallas, Texas, United States
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Denton, Texas, United States
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Houston, Texas, United States
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Hampton, Virginia, United States
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Graz, Austria
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Linz, Austria
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Vienna, Austria
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Aalst, Belgium
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Brussels, Belgium
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Charleroi, Belgium
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Ghent, Belgium
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Wilrijk, Belgium
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Angers, France
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Bordeaux, France
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Caen Cédex 05, France
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Dijon, France
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Lyon, France
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Nice, France
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Nîmes, France
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Paris, France
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Saint-Herblain, France
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Suresnes, France
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Villejuif, France
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Berlin, Germany
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Erlangen, Germany
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Essen, Germany
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Freiburg im Breisgau, Germany
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Göttingen, Germany
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Greifswald, Germany
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Hamburg, Germany
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Hanover, Germany
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Heidelberg, Germany
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München, Germany
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Münster, Germany
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Regensburg, Germany
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Straubing, Germany
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Weiden/Opf, Germany
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Bangalore, India
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Kolkata, India
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Mira Road (East), India
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Nadiād, India
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Beer Yaakov, Israel
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Beersheba, Israel
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Haifa, Israel
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Kfar Saba, Israel
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Petah Tikva, Israel
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Tel Aviv, Israel
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Chisinau, Moldova
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Bucharest, Romania
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Cluj-Napoca, Romania
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Craiova, Romania
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Iași, Romania
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Barnaul, Russia
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Moscow, Russia
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Omsk, Russia
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Pyatigorsk, Russia
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Saint Petersburg, Russia
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Ufa, Russia
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Daejeon, South Korea
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Goyang-si, South Korea
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Incheon, South Korea
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Seoul, South Korea
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Badalona, Spain
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Barcelona, Spain
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Madrid, Spain
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Málaga, Spain
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Pamplona, Spain
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Sabadell, Spain
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Santander, Spain
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Santiago de Compostela, Spain
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Seville, Spain
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Valencia, Spain
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Taichung, Taiwan
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Tainan, Taiwan
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Taipei, Taiwan
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Taoyuan, Taiwan
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Istanbul, Turkey (Türkiye)
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Blackburn, United Kingdom
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Dundee, United Kingdom
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Essex, United Kingdom
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London, United Kingdom
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Metropolitan Borough of Wirral, United Kingdom
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Plymouth, United Kingdom
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Sutton, United Kingdom